Fig. 6. Nanoprobe-based, ultrasensitive CRISPR biosensor. (a) CRISPR-dCas9-mediated gold magnetic nanoparticle, ultra-sensitive SERS based detection for superbug infection. Reproduced with the permission from [36], Copyright 2020, American Chemical Society. (b) Coupling gold nanoparticle-mediated metalenhanced fluorescence (MEF) and CRISPR-Cas12a for nucleic acid detection without amplification. Reproduced with the permission from [37], Copyright 2021, American Chemical Society.

Applied Science and Convergence Technology 2022;31:40~45 https://doi.org/10.5757/ASCT.2022.31.2.40

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