Fig. 5. Drug evaluation using 3D bioprinting technology. (a) Schematic diagram showing the formation of bulk and drug-resistant cancer spheroids using 3D bioprinting and imaging analysis of embedded spheroids. Reproduced with the permission from [
51], Copyright 2022, Elsevier. (b) Photographic image of a ten-layer printed scaffold with Ink H4-RGD. Reproduced with the permission from [
52], Copyright 2021, Nature. (c) Cancer model HepG2 and keratinocyte HaCaT cells were cultured in 3D and 2D culture systems. Reproduced with the permission from [
53], Copyright 2020, MDPI. (d). Schematic diagram of a polydimethylsiloxane multichannel cell chip. Reproduced with the permission from [
54], Copyright 2021, MDPI. (e) Schematics showing the procedure of fabricating endothelialized myocardium using a 3D bioprinting strategy. Reproduced with the permission from [
55], Copyright 2016, Elsevier.
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