Non-thermal biocompatible plasma (NBP), which generates various reactive species, is being actively researched in the field of aesthetic medicine for applications such as microorganism inactivation, skin regeneration, inflammation treatment, and drug absorption. This study evaluates the effectiveness of NBP and cosmetics in treating acne-prone skin by utilizing the sterilizing and regenerative effects of plasma. The present study involves 21 adult men and women over the age of 20 who require acne treatment. Participants use NBP and cosmetics after washing their faces in the morning and evening for six weeks. After six weeks, the global acne grading system scores show a 26.91 % reduction in acne severity and a 25.11 % reduction in sebum levels. The results confirm that NBP is effective in improving acne and reducing sebum. No adverse skin reactions are observed during the study period. Notably, NBP applies floating electrode-dielectric barrier discharge technology, which promotes the removal of acne-causing bacteria and skin regeneration. This study suggests that NBP is an effective method for acne treatment.

Keywords: Non-thermal biocompatible plasma, Floating electrode-dielectric barrier discharge, Acne treatment, Skin rejuvenation